Computational Systems Biology Approaches in Cancer Research
暫譯: 癌症研究中的計算系統生物學方法

Kuperstein, Inna, Barillot, Emmanuel

  • 出版商: CRC
  • 出版日期: 2019-09-16
  • 售價: $3,630
  • 貴賓價: 9.5$3,449
  • 語言: 英文
  • 頁數: 167
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0367344211
  • ISBN-13: 9780367344214
  • 海外代購書籍(需單獨結帳)

相關主題

商品描述

Praise for Computational Systems BiologyApproaches in Cancer Research:

"Complex concepts are written clearly and with informative illustrations and useful links. The book is enjoyable to read yet provides sufficient depth to serve as a valuable resource for both students and faculty."

-- Trey Ideker, Professor of Medicine, UC Xan Diego, School of Medicine

"This volume is attractive because it addresses important and timely topics for research and teaching on computational methods in cancer research. It covers a broad variety of approaches, exposes recent innovations in computational methods, and provides acces to source code and to dedicated interactive web sites."

-- Yves Moreau, Department of Electrical Engineering, SysBioSys Centre for Computational Systems Biology, University of Leuven

With the availability of massive amounts of data in biology, the need for advanced computational tools and techniques is becoming increasingly important and key in understanding biology in disease and healthy states. This book focuses on computational systems biology approaches, with a particular lens on tackling one of the most challenging diseases - cancer.  The book provides an important reference and teaching material in the field of computational biology in general and cancer systems biology in particular.

The book presents a list of modern approaches in systems biology with application to cancer research and beyond. It is structured in a didactic form such that the idea of each approach can easily be grasped from the short text and self-explanatory figures. The coverage of topics is diverse: from pathway resources, through methods for data analysis and single data analysis to drug response predictors, classifiers and image analysis using machine learning and artificial intelligence approaches.

Features

  • Up to date using a wide range of approaches
  • Applicationexample in each chapter

  • Online resources with useful applications'

商品描述(中文翻譯)

對於《計算系統生物學在癌症研究中的方法》的讚譽:

「複雜的概念以清晰的方式撰寫,並附有資訊豐富的插圖和有用的連結。這本書讀起來令人愉快,同時提供了足夠的深度,成為學生和教職員的寶貴資源。」

-- Trey Ideker,加州大學聖地牙哥分校醫學院教授

「這本書吸引人之處在於它針對癌症研究中的計算方法,探討了重要且及時的主題,涵蓋了各種方法,揭示了計算方法的最新創新,並提供了源代碼和專門的互動網站的訪問。」

-- Yves Moreau,魯汀大學電機工程系,SysBioSys計算系統生物學中心

隨著生物學中大量數據的可用性,對於先進計算工具和技術的需求變得越來越重要,這對於理解疾病和健康狀態中的生物學至關重要。本書專注於計算系統生物學的方法,特別著眼於應對最具挑戰性的疾病之一——癌症。這本書在計算生物學領域,特別是在癌症系統生物學方面,提供了重要的參考和教學材料。

本書列出了現代系統生物學在癌症研究及其他領域的應用方法。其結構採用教學形式,使每種方法的概念能夠從簡短的文字和自我解釋的圖形中輕易理解。涵蓋的主題多樣:從途徑資源、數據分析方法和單一數據分析,到藥物反應預測器、分類器以及使用機器學習和人工智慧方法的影像分析。

特色

  • 使用各種最新方法
  • 每章的應用範例


  • 提供有用應用的線上資源



作者簡介

Inna Kuperstein is a researcher at Institut Curie, Paris, France, she is a coordinator of the Atlas of Cancer Signalling Networks (ACSN) project for construction and analysis of detailed signalling maps, development of tools and modelling the maps to predict drug response. She participates in multidisciplinary projects to decipher cell mechanisms rewiring in cancer.

Emmanuel Barillot is the head of the Cancer and Genome: Bioinformatics, Biostatistics and Epidemiology of a Complex System department and scientific director of the bioinformatics platform at Institut Curie. His research focuses on methodological development and statistical analysis of high-throughput biological data and modeling with the aim to improve therapeutic treatments of cancer.

作者簡介(中文翻譯)

Inna Kuperstein 是法國巴黎居里研究所的研究員,她是癌症信號網絡圖譜 (Atlas of Cancer Signalling Networks, ACSN) 項目的協調員,負責構建和分析詳細的信號圖,開發工具並建模這些圖以預測藥物反應。她參與多學科項目,以解碼癌症中細胞機制的重組。

Emmanuel Barillot 是癌症與基因組:生物資訊學、生物統計學和複雜系統流行病學部門的負責人,也是居里研究所生物資訊平台的科學主任。他的研究專注於高通量生物數據的方法學開發和統計分析,以及建模,旨在改善癌症的治療方法。