商品描述
First published in 1992. Dermal Immune System discusses the structural and functional characterizations of the dermal immune system, including dermal dendritic cells, monocyte/macrophages, microvascular endothelial cells, pericytes, veil cells, fibroblasts, mast cells, dermal T lymphocytes, and peripheral nerve endings. This information is invaluable for gaining an understanding of how multicellular complex networks interface within the dermis and between the exogenous environment and endogenous milieu. Specific examples are provided that document the involvement of the dermal immune system in the pathophysiology of several skin diseases that result from perturbation of normal cutaneous homeostasis.
Dermal Immune System is an excellent reference volume that should always be close at hand for immunologists, cell biologists, investigative dermatologists, pathologists, and clinicians involved in the care of patients with skin disease.
商品描述(中文翻譯)
首次出版於1992年。《皮膚免疫系統》討論了皮膚免疫系統的結構和功能特徵，包括皮膚樹突細胞、單核細胞/巨噬細胞、微血管內皮細胞、周細胞、膜細胞、成纖維細胞、肥大細胞、皮膚T淋巴細胞和周邊神經末梢。這些資訊對於理解多細胞複雜網絡如何在真皮內部以及外部環境與內部環境之間進行交互至關重要。書中提供了具體的例子，記錄了皮膚免疫系統在幾種由正常皮膚穩態擾動引起的皮膚疾病的病理生理學中的參與。
《皮膚免疫系統》是一本優秀的參考書，對於免疫學家、細胞生物學家、研究性皮膚科醫生、病理學家以及參與皮膚疾病患者護理的臨床醫生來說，應該隨時放在手邊。
作者簡介
Brian J. Nickoloff M.D., Ph.D., is an Associate Professor in the Departments of Pathology and Dermatology at the University of Michigan Medical School, Ann Arbor, Michigan. Dr. Nickoloff graduated in 1974 from Kalamazoo College with a B.S. degree in biology (cum laude) and obtained his M.D. degree in 1979 from Wayne State University, Detroit, followed by his Ph.D. degree in Biochemistry. After completing an internship in internal medicine at Harbor General Hospital-UCLA, he finished his anatomic pathology training at the Brigham and Womens Hospital-Harvard University, Boston. After a fellowship year in the Department of Dermatology at Stanford University, he stayed on and became the Director of Dermatopathology and an Assistant Professor of Dermatology and Pathology until 1986. In 1987, he relocated to Ann Arbor and became Associate Professor of Pathology and Dermatology at The University of Michigan in 1990. Dr. Nickoloff is a member of the American Association of Pathologists, Society for Investivative Dermatology, American Society of Dermatopathology, International Society of Dermatopathology, American Association for the Advancement for Science, and the American Federation of Clinical Research. He serves on the editorial board of The American Journal of Dermatopathology, Journal of Cutaneous Pathology, Journal of the Academy of Dermatology, Journal of Dermatological Science, and American Journal of Pathology. As of 1991, he was the principal investigator of four different National Institutes of Health (NIH) grants and is a current member of the NIH-General Medicine-A study section. Dr. Nickoloff has presented over 40 invited lectures at both National and International Meetings. He has published over 130 research papers and is the author, or co-author, of a dozen book chapters. Beyond his primary patient-care related activities, his current major research as it relates to immunod-ermatology includes elucidation of the cytokine network in psoriasis; the role of adhesion molecules, chemotactic polypeptides, and growth factors in allergic contact dermatitis; and the role of dermal dendrocytes in AIDS-related skin diseases such as Kaposi's sarcoma and psoriasis.
作者簡介(中文翻譯)
布萊恩·J·尼科洛夫醫學博士、哲學博士，是密西根大學醫學院病理學與皮膚科的副教授，位於密西根州安娜堡。尼科洛夫博士於1974年從卡拉馬祖學院獲得生物學學士學位（優等生），並於1979年從底特律的韋恩州立大學獲得醫學博士學位，隨後獲得生物化學的哲學博士學位。在加州大學洛杉磯分校的哈伯總醫院完成內科實習後，他在哈佛大學的布萊根與婦女醫院完成了解剖病理學的培訓。之後，他在斯坦福大學皮膚科進行了一年的研究員培訓，並留任成為皮膚病理學主任及皮膚科和病理學的助理教授，直到1986年。1987年，他搬到安娜堡，並於1990年成為密西根大學病理學與皮膚科的副教授。尼科洛夫博士是美國病理學會、皮膚病研究學會、美國皮膚病理學會、國際皮膚病理學會、美國科學促進會及美國臨床研究聯合會的成員。他擔任《美國皮膚病理學雜誌》、《皮膚病理學雜誌》、《皮膚科學學院雜誌》、《皮膚科學雜誌》和《美國病理學雜誌》的編輯委員會成員。自1991年以來，他是四項不同國家衛生研究院（NIH）資助的主要研究者，並且是NIH一般醫學研究小組的現任成員。尼科洛夫博士在國內外會議上發表了超過40場受邀演講。他已發表超過130篇研究論文，並且是十幾本書章的作者或合著者。除了主要的病人護理相關活動外，他目前的主要研究與免疫皮膚病學有關，包括闡明銀屑病中的細胞因子網絡；粘附分子、趨化多肽和生長因子在過敏性接觸性皮膚炎中的作用；以及真皮樹突細胞在與艾滋病相關的皮膚疾病（如卡波西肉瘤和銀屑病）中的作用。
