Learning from Disease in Pets: A 'One Health' Model for Discovery
暫譯: 從寵物疾病中學習:一個「一體健康」的發現模型

Krimins, Rebecca A.

  • 出版商: CRC
  • 出版日期: 2020-11-26
  • 售價: $9,380
  • 貴賓價: 9.5$8,911
  • 語言: 英文
  • 頁數: 294
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0367173166
  • ISBN-13: 9780367173166
  • 海外代購書籍(需單獨結帳)

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商品描述

Learning from Disease in Pets: A 'One Health' Model for Discovery is the first encompassing reference guide for veterinarians, researchers and physicians on conducting studies using spontaneous models of disease in animals. The study of naturally occurring disease in (pet) animals can help model our understanding of the biology, prevention and therapy of human and animal diseases. Studies of pet dogs, for instance, can aid treatment of complex medical problems such as cancer, orthopedic, cardiopulmonary, and neuro-inflammatory diseases, and zoonotic infections. Each chapter within this novel cross-species approach is contributed by a leader, or leaders, in their field of research.

Using clinical trials to learn how pets with real diseases respond to therapy can lead to breakthroughs in human medicine, as well as benefiting pets suffering from otherwise debilitating illness. Despite similarities of diseases across species, there are very few spontaneous models of disease used in research compared with models where disease is induced in healthy laboratory animals. Many medical researchers and veterinarians have a multitude of questions regarding how to use naturally occurring diseases in pets for the discovery of treatments and diagnostics: this book will demonstrate how to safely make this happen.

This book encourages veterinarians to build on and disseminate existing findings for the wider benefit of pets and humans. Many pets suffering from incurable illnesses may benefit from clinical trials; the book includes a section on the imperative communication styles necessary within the research environment and with clients, a compelling discussion on the ethics of using pets in veterinary clinical research, comprehensive tables of diseases that spontaneously occur in animals and humans, the regulatory requirements necessary to move therapy from benchside research to patient bedside, as well as intricate details on how to design a robust clinical study.

 

 

商品描述(中文翻譯)

《從寵物疾病中學習:一個「一健康」的發現模型》是第一本針對獸醫、研究人員和醫生的全面參考指南,旨在使用動物自發性疾病模型進行研究。研究(寵物)動物中自然發生的疾病可以幫助我們理解人類和動物疾病的生物學、預防和治療。例如,對寵物狗的研究可以幫助治療複雜的醫療問題,如癌症、骨科、心肺和神經炎症疾病,以及人畜共通感染。這本書中的每一章都是由其研究領域的領導者貢獻的。

利用臨床試驗來了解患有真實疾病的寵物對治療的反應,可以在人體醫學上帶來突破,同時也能惠及那些遭受其他致殘性疾病的寵物。儘管不同物種之間的疾病有相似之處,但與在健康實驗室動物中誘發疾病的模型相比,使用自發性疾病模型的研究卻非常少。許多醫學研究人員和獸醫對如何利用寵物中自然發生的疾病來發現治療和診斷方法有許多疑問:這本書將展示如何安全地實現這一目標。

本書鼓勵獸醫在現有研究成果的基礎上進行擴展和傳播,以更廣泛地造福寵物和人類。許多患有不治之症的寵物可能會從臨床試驗中受益;本書包括一個關於在研究環境和與客戶之間所需的有效溝通風格的部分,對於在獸醫臨床研究中使用寵物的倫理問題進行了引人入勝的討論,提供了動物和人類中自發性疾病的綜合表格,以及將治療從實驗室研究轉移到病人床邊所需的監管要求,還有如何設計穩健臨床研究的詳細資訊。

作者簡介

Dr. Rebecca Krimins is an Assistant Professor in the Johns Hopkins Medicine Department of Radiology and Radiological Science, with additional appointments in the Department of Anesthesiology and Critical Care Medicine and the Department of Molecular and Comparative Pathobiology. A native of Annapolis, Maryland, Dr. Krimins completed her veterinary anesthesia and analgesia residency at the Purdue University School of Veterinary Medicine. Dr. Krimins has more than 15 years of experience in managing critically ill patients during advanced imaging procedures and conducting cutting-edge clinical studies. Dr. Krimins' specialty in veterinary anesthesia, sedation and pain management in combination with her experience in directing advanced clinical research offers each veterinary patient the best opportunities for diagnosis and therapy. Dr. Krimins works closely with each patient's personal veterinarian and pet family to ensure accurate and timely results that are crucial for therapeutic options. The Veterinary Clinical Trials Network at Johns Hopkins University is designed to leverage the expertise and platforms available at Johns Hopkins University in order to transform newly discovered diagnostics and therapeutics into real-life practical approaches that benefit veterinary patients

作者簡介(中文翻譯)

Rebecca Krimins 博士是約翰霍普金斯醫學院放射科及放射科學的助理教授,並在麻醉學及重症醫學系以及分子與比較病理學系擔任其他職務。Krimins 博士是馬里蘭州安納波利斯人,於普渡大學獸醫學院完成獸醫麻醉及鎮痛的住院醫師訓練。Krimins 博士在管理重症病患進行先進影像檢查及進行前沿臨床研究方面擁有超過 15 年的經驗。Krimins 博士在獸醫麻醉、鎮靜及疼痛管理方面的專長,加上她在指導先進臨床研究的經驗,為每位獸醫病患提供最佳的診斷和治療機會。Krimins 博士與每位病患的個人獸醫及寵物家庭密切合作,以確保準確及時的結果,這對於治療選擇至關重要。約翰霍普金斯大學的獸醫臨床試驗網絡旨在利用約翰霍普金斯大學的專業知識和平台,將新發現的診斷和治療方法轉化為實際可行的方案,以造福獸醫病患。