Protein Kinases in Drug Discovery, 124
暫譯: 藥物發現中的蛋白激酶,124

Donev, Rossen

  • 出版商: Academic Press
  • 出版日期: 2021-02-25
  • 售價: $6,190
  • 貴賓價: 9.5$5,881
  • 語言: 英文
  • 頁數: 350
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0323853137
  • ISBN-13: 9780323853132
  • 海外代購書籍(需單獨結帳)

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商品描述

Protein Kinases in Drug Discovery, Volume 124 discusses the latest information on protein kinases and how they modify other proteins by chemically adding phosphate groups to them. New chapters in this release include Transport Proteins and AMPs: Implications in Human Disease, Protein kinase CK2 inhibition as a pharmacological strategy, Emerging role of Protein kinase in diabetes mellitus: From Mechanism to therapy, Dual Roles of ATP-binding site in Protein Kinases: Orthosteric inhibition and Allosteric Regulation, Pseudokinases in drug discovery and development: progress, challenges and future prospects, Comparison of knowledge-based vs. combinatorial peptide library approaches for the identification of protein kinase substrates, and more.

商品描述(中文翻譯)

藥物發現中的蛋白激酶,第124卷》討論了蛋白激酶的最新資訊,以及它們如何通過化學方式將磷酸基團添加到其他蛋白質上。這次發行的新章節包括:運輸蛋白和抗微生物肽(AMPs):對人類疾病的影響、蛋白激酶CK2抑制作為藥理策略、蛋白激酶在糖尿病中的新興角色:從機制到療法、ATP結合位點在蛋白激酶中的雙重角色:正位抑制和變構調控、藥物發現和開發中的偽激酶:進展、挑戰和未來展望、基於知識的蛋白激酶底物識別與組合肽庫方法的比較,等等。