Applications of Heterocycles in the Design of Drugs and Agricultural Products, 134
暫譯: 雜環化合物在藥物與農產品設計中的應用,134

Meanwell, Nicholas A., Lolli, Marco L.

  • 出版商: Academic Press
  • 出版日期: 2021-06-14
  • 售價: $8,720
  • 貴賓價: 9.5$8,284
  • 語言: 英文
  • 頁數: 332
  • 裝訂: Hardcover - also called cloth, retail trade, or trade
  • ISBN: 0128201819
  • ISBN-13: 9780128201817
  • 海外代購書籍(需單獨結帳)

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商品描述

Applications of Heterocycles in the Design of Drugs and Agricultural Products, Volume 134 in the Advances in Heterocyclic Chemistry series represents the most definitive series in the field - one of great importance to organic chemists, polymer chemists, and many biological scientists. Chapters in this updated volume cover Hydroxy azoles as carboxylic acid bioisosteres, Cyclic sulfoxides and sulfones in drug design, Thiazoles and topological control in drug design, Applications of fused pyrrolidine [3.3.0] heterocycles in drug design, 1,4 Disubstituted and 1,4,5 trisubstituted-1,2,3-triazoles in drug discovery and development: from the flask to the clinic, and Conformationally restricted [3.2.2]- and [3.2.1]-3-azabicyclic diamines.

Because biology and organic chemistry increasingly intersect, the associated nomenclature is being used more frequently in explanations. Written by established authorities in the field from around the world, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding of how chemistry drives the preparation and useful properties of heterocyclic compounds.

商品描述(中文翻譯)

《異環化學進展系列,第134卷:異環的應用於藥物和農產品設計》是該領域最具權威性的系列之一,對有機化學家、高分子化學家以及許多生物科學家來說具有重要意義。本更新卷中的章節涵蓋了羥基噁唑作為羧酸生物等效物、環狀亞磺醯和亞磺酮在藥物設計中的應用、噻唑及其在藥物設計中的拓撲控制、融合吡咯烷 [3.3.0] 異環在藥物設計中的應用、1,4-二取代和1,4,5-三取代-1,2,3-三唑在藥物發現和開發中的應用:從燒瓶到臨床,以及構象受限的 [3.2.2]-和 [3.2.1]-3-氮雙環二胺。

隨著生物學和有機化學的交集日益增多,相關的命名法在解釋中被更頻繁地使用。這本由來自全球的領域內權威人士撰寫的綜合性評論,結合了描述性的合成化學和機制洞察,幫助讀者理解化學如何推動異環化合物的製備及其有用特性。

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