Organ on a Chip: Convergence of Advanced Materials, Cells, and Microscale Technologies
暫譯: 晶片上的器官:先進材料、細胞與微型技術的融合
Hoeng, Julia, Bovard, David, Peitsch, Manuel
- 出版商: Academic Press
- 出版日期: 2019-11-11
- 售價: $6,420
- 貴賓價: 9.5 折 $6,099
- 語言: 英文
- 頁數: 400
- 裝訂: Quality Paper - also called trade paper
- ISBN: 0128172029
- ISBN-13: 9780128172025
海外代購書籍(需單獨結帳)
商品描述
Organ on a Chip: Convergence of Advanced Materials, Cells, and Microscale Technologies contains chapters from world-leading researchers in the field of organ on a chip development and applications, with perspectives from life sciences, medicine, physiology and engineering. The book contains an overview of the field, with sections covering the major organ systems and currently available technologies, platforms and methods. As readers may also be interested in creating biochips, materials and engineering best practice, these topics are also described.
Users will learn about the limitations of 2D in-vitro models and the available 3D in-vitro models (what benefits they offer and some examples). Finally, the MOC section shows how the organ on a chip technology can be adapted to improve the physiology of in-vitro models.
- Includes case studies of other organs on a chip that have been developed and successfully used
- Provides insights into functional microphysiological organ on a chip platforms for toxicity and efficacy testing, along with opportunities for translational medicine
- Presented fields (PK/PD, physiology, medicine, safety) are given a definition followed by the challenges and potential of organs on a chip
商品描述(中文翻譯)
《晶片上的器官:先進材料、細胞與微型技術的融合》包含了來自於晶片上器官開發與應用領域的世界領先研究者的章節,涵蓋生命科學、醫學、生理學和工程學的觀點。本書提供了該領域的概述,並包含有關主要器官系統及目前可用技術、平台和方法的部分。由於讀者可能也對創建生物晶片、材料和工程最佳實踐感興趣,因此這些主題也有描述。
使用者將了解2D體外模型的限制以及可用的3D體外模型(它們提供的好處及一些範例)。最後,MOC部分展示了如何調整晶片上器官技術以改善體外模型的生理特性。
- 包含其他已開發並成功使用的晶片上器官的案例研究
- 提供功能性微生理晶片上器官平台在毒性和療效測試中的見解,以及轉化醫學的機會
- 所呈現的領域(藥物動力學/藥效學、生理學、醫學、安全性)都給予定義,並隨後討論晶片上器官的挑戰與潛力